Caspase 6 antibody (Middle Region)

Catalog No. ABIN929109

The Rabbit Polyclonal anti-Caspase 6 antibody (ABIN929109) specifically detects Caspase 6 in WB. The antibody is reactive with Human samples.

Quick Overview for Caspase 6 antibody (Middle Region) (ABIN929109)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Caspase 6 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: CASP6 antibody was raised in rabbit using the middle region of CASP6 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CASP6 Blocking Peptide, (ABIN5612634), is also available for use as a blocking control in assays to test for specificity of this CASP6 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Alternative Name: CASP6

Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. Synonyms: Polyclonal CASP6 antibody, Anti-CASP6 antibody, caspase 6, apoptosis-related cysteine peptidase antibody, MCH2 antibody.

Pathways: Apoptosis, Caspase Cascade in Apoptosis