Caspase 6 antibody (AA 7-27)

Catalog No. ABIN3030314

The Rabbit Polyclonal anti-Caspase 6 antibody is suitable to detect Caspase 6 in samples from Mouse and Rat. It has been validated for WB, IHC (p) and IHC (fro).

Quick Overview for Caspase 6 antibody (AA 7-27) (ABIN3030314)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Caspase 6 Antibody

Binding Specificity: AA 7-27

Purpose: Caspase-6 Antibody

Purification: Antigen affinity

Immunogen: Amino acids 7-27 (FYRSREVLDPAEQYKMDHKRR-rat) were used as the immunogen for this Caspase-6 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Caspase-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Caspase-6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Alternative Name: Caspase-6

Background: Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease family. Using radiation hybrid mapping, the CASP6 gene was localized to human chromosome 4q25-q26. It functions as a downstream enzyme in the caspase activation cascade, and can cleave Lamin A to its signature apoptotic fragment.

UniProt: O35397

Pathways: Apoptosis, Caspase Cascade in Apoptosis