Caspase 7 antibody (N-Term)

Catalog No. ABIN929110

This Rabbit Polyclonal antibody specifically detects Caspase 7 in WB. It exhibits reactivity toward Human.

Quick Overview for Caspase 7 antibody (N-Term) (ABIN929110)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Caspase 7 Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: CASP7 antibody was raised in rabbit using the N terminal of CASP7 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CASP7 Blocking Peptide, (ABIN5612635), is also available for use as a blocking control in assays to test for specificity of this CASP7 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Alternative Name: CASP7

Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. Synonyms: Polyclonal CASP7 antibody, Anti-CASP7 antibody, caspase 7, apoptosis-related cysteine peptidase antibody, CMH-1 antibody, ICE-LAP3 antibody, MCH3 antibody.

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity