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Caspase 7 antibody

CASP7 Reactivity: Human, Mouse, Rat, Monkey, Pig, Dog, Hamster, Rabbit, Sheep WB, IHC, IHC (p) Host: Mouse Monoclonal 7-1-11 unconjugated
Catalog No. ABIN462356
  • Target See all Caspase 7 (CASP7) Antibodies
    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
    Reactivity
    • 78
    • 52
    • 27
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Monkey, Pig, Dog, Hamster, Rabbit, Sheep
    Host
    • 76
    • 12
    • 1
    Mouse
    Clonality
    • 74
    • 15
    Monoclonal
    Conjugate
    • 61
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caspase 7 antibody is un-conjugated
    Application
    • 85
    • 30
    • 26
    • 20
    • 14
    • 13
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Brand
    IHC-plus™
    Specificity
    Detects an ~37 kD protein, corresponding to the apparent molecular mass of the caspase-7 on SDS-PAGE immunoblots, in samples from human, mouse, rat, monkey, dog, sheep, rabbit, pig and hamster origins. This antibody recognizes the unprocessed pro-caspase-7 (p35), caspase-7 lacking the short amino- terminal pro domain (32 kD) and the fully processed caspase-7 (p19) in apoptotic cell extracts.
    Purification
    Protein G purified
    Immunogen
    Recombinant human caspase-7 full length protein.

    Type of Immunogen: Recombinant protein
    Clone
    7-1-11
    Isotype
    IgG
    Top Product
    Discover our top product CASP7 Primary Antibody
  • Application Notes
    Approved: IHC, IHC-P (10 μg/mL), WB

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS (10 mM sodium phosphate,  pH 7.2, 50 mM sodium chloride, 0.1 mM PMSF). Sourced in Ascites.
    Preservative
    PMSF
    Handling Advice
    avoid freeze thaw cycles. For maximum product recovery, after thawing, centrifuge the product vial before removing cap.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. For maximum product recovery, after thawing, centrifuge the product vial before removing cap.
  • Target
    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
    Alternative Name
    CASP7 / Caspase 7 (CASP7 Products)
    Synonyms
    xCaspase-7 antibody, caspase-7 antibody, caspase7 antibody, cmh-1 antibody, ice-lap3 antibody, mch3 antibody, CASP7 antibody, AI314680 antibody, CMH-1 antibody, ICE-IAP3 antibody, Mch3 antibody, mCASP-7 antibody, CASP-7 antibody, ICE-LAP3 antibody, LICE2 antibody, MCH3 antibody, Caspase-7 antibody, MCH3/SCA-2 antibody, SCA-2 antibody, caspase 7 antibody, caspase-7 antibody, caspase 7 S homeolog antibody, CASP7 antibody, xcaspase-7 antibody, casp7 antibody, casp7.S antibody, Casp7 antibody
    Background
    Name/Gene ID: CASP7
    Subfamily: Cysteine C14
    Family: Protease

    Synonyms: CASP7, Apoptotic protease Mch-3, Caspase 7, Caspase-7, ICE-LAP3, LICE2, MCH3, ICE-like apoptotic protease 3, CASP-7, CMH-1
    Gene ID
    840
    UniProt
    P55210
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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