LAG3 antibody (C-Term)

Catalog No. ABIN929141

The Rabbit Polyclonal anti-LAG3 antibody is suitable to detect LAG3 in samples from Human. It has been validated for WB.

Quick Overview for LAG3 antibody (C-Term) (ABIN929141)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAG3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LAG3 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: LAG3 antibody was raised in rabbit using the C terminal of LAG3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

LAG3 Blocking Peptide, (ABIN938646), is also available for use as a blocking control in assays to test for specificity of this LAG3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Alternative Name: LAG3

Background: Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. Synonyms: Polyclonal LAG3 antibody, Anti-LAG3 antibody, lymphocyte-activation gene 3 antibody, CD223 antibody.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints