HEYL antibody

Catalog No. ABIN931114

This Mouse Monoclonal antibody specifically detects HEYL in DB. It exhibits reactivity toward Human.

Quick Overview for HEYL antibody (ABIN931114)

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HEYL antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 3555C3a

Product Details anti-HEYL Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: HEYL antibody was raised in mouse using recombinant Human Hairy/Enhancer-Of-Split Related With Yrpw Motif-Like

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: HEYL antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for HEYL

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Alternative Name: HEYL

Background: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. Synonyms: Monoclonal HEYL antibody, Anti-HEYL antibody, Hairy/enhancer-of-split related with YRPW motif-like protein antibody, HRT3 antibody, MGC12623 antibody.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling