CD40 antibody

Catalog No. ABIN931290

The Mouse Monoclonal anti-CD40 antibody (Clone 9G10) (ABIN931290) specifically detects CD40 in ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for CD40 antibody (ABIN931290)

Target: CD40

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Clone: 9G10

Product Details anti-CD40 Antibody

Immunogen: CD40 antibody was raised in Mouse using a purified recombinant fragment of CD40 expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IF: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background: CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. Deficiency can cause Hyper-IgM syndrome type 3. Synonyms: Monoclonal CD40 antibody, Anti-CD40 antibody, Cluster of differentiation 40 antibody, Soluble CD40 Ligand antibody, TNFSF5 antibody, TRAP antibody, CD154 antibody, gp39 antibody, T-BAM antibody.

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints