CD40 antibody
-
- Target See all CD40 Antibodies
- CD40
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This CD40 antibody is un-conjugated
-
Application
- ELISA, Immunofluorescence (IF)
- Immunogen
- CD40 antibody was raised in Mouse using a purified recombinant fragment of CD40 expressed in E. coli as the immunogen.
- Clone
- 9G10
- Isotype
- IgG1
- Top Product
- Discover our top product CD40 Primary Antibody
-
-
- Application Notes
-
ELISA: 1:10,000, IF: 1:200-1:1000
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
-
- Target
- CD40
- Alternative Name
- CD40 (CD40 Products)
- Synonyms
- Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
- Background
- CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. Deficiency can cause Hyper-IgM syndrome type 3. Synonyms: Monoclonal CD40 antibody, Anti-CD40 antibody, Cluster of differentiation 40 antibody, Soluble CD40 Ligand antibody, TNFSF5 antibody, TRAP antibody, CD154 antibody, gp39 antibody, T-BAM antibody.
- Pathways
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
-