IL-10 antibody

Catalog No. ABIN3210005

This Mouse Monoclonal antibody specifically detects IL-10 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for IL-10 antibody (ABIN3210005)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3C12C12

Product Details anti-IL-10 Antibody

Purification: Purified antibody.

Immunogen: IL10 antibody was raised in Mouse using a purified recombinant fragment of human IL-10 expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified antibody supplied in PBS containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Alternative Name: IL10

Background: IL10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL10 inhibits the expression of proinflammatory cytokines such as IL1 and TNFa. Like IL4, IL10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL10 active on Mouse cells, but Mouse IL10 is inactive on human cells. Synonyms: Monoclonal IL10 antibody, Anti-IL10 antibody, IL-10 antibody, Interleukin 10 antibody, B-TCGF antibody, CSIF antibody, TGIF antibody.

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints