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Actl7b antibody (N-Term)

The Rabbit Polyclonal anti-Actl7b antibody has been validated for WB and EIA. It is suitable to detect Actl7b in samples from Human.
Catalog No. ABIN950264

Quick Overview for Actl7b antibody (N-Term) (ABIN950264)

Target

See all Actl7b Antibodies
Actl7b (Actin-Like 7b (Actl7b))

Reactivity

  • 30
  • 12
  • 3
  • 1
  • 1
  • 1
Human

Host

  • 34
  • 3
  • 2
Rabbit

Clonality

  • 38
  • 1
Polyclonal

Conjugate

  • 19
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Actl7b antibody is un-conjugated

Application

  • 29
  • 24
  • 4
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Binding Specificity

    • 10
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 68-97, N-Term

    Specificity

    This antibody reacts to ACTL7B.

    Cross-Reactivity (Details)

    Species reactivity (tested):Human.

    Purification

    Affinity chromatography on Protein A

    Immunogen

    KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human ACTL7B

    Isotype

    Ig Fraction
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) sodium azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    Actl7b (Actin-Like 7b (Actl7b))

    Alternative Name

    ACTL7B

    Background

    The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.Synonyms: Actin-like protein 7B, Actin-like-7-beta

    Gene ID

    10880

    NCBI Accession

    NP_006677
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