Adenosine Deaminase (ADA) (C-Term), (AA 294-322) antibody

Details for Product No. ABIN950276
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Antigen
Synonyms ADA-like, xada, ADA, CG11994, Dmel\\CG11994, DrosADA, dADA, ADGDF-A, ADGF-A, Adgf-a, CG5992, Dmel\\CG5992, adgf-a, adgfa
Epitope
C-Term, AA 294-322
(6), (6), (5), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(45), (38), (20), (19), (12), (1), (1)
Host
Rabbit
(62), (13)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(60), (39), (13), (11), (10), (10), (10), (5), (5), (4), (4), (3), (3), (3), (1), (1)
Pubmed 3 references available
Catalog no. ABIN950276
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

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Immunogen KLH conjugated synthetic peptide between 294-322 amino acids from the C-terminal region of human ADA
Specificity This antibody reacts to Adenosine deaminase.
Purification Affinity chromatography on Protein A
Background This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
Alternate names: Adenosine aminohydrolase
Gene ID 100
NCBI Accession NP_000013
Research Area Enzymes
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Gloria-Bottini, Banci, Saccucci et al.: "The interaction of ACP1, ADA1, diabetes and gender in coronary artery disease." in: The American journal of the medical sciences, Vol. 340, Issue 2, pp. 103-8, 2010 (PubMed).

Levine, Figueiredo, Lee et al.: "A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 7, pp. 1812-21, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Hosts (62), (13)
Reactivities (45), (38), (20), (19), (12), (1), (1)
Applications (60), (39), (13), (11), (10), (10), (10), (5), (5), (4), (4), (3), (3), (3), (1), (1)
Conjugates (7), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (6), (5), (3), (2), (1), (1), (1), (1), (1)
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