CLEC18A antibody (C-Term)

Catalog No. ABIN951563

The Rabbit Polyclonal anti-CLEC18A antibody has been validated for WB and IHC (p). It is suitable to detect CLEC18A in samples from Human.

Quick Overview for CLEC18A antibody (C-Term) (ABIN951563)

Target: CLEC18A (C-Type Lectin Domain Family 18, Member A (CLEC18A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC18A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CLEC18A Antibody

Binding Specificity: AA 345-375, C-Term

Specificity: This antibody detects CLEC18A at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of Human CLEC18A Genename: CLEC18A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CLEC18A

Target: CLEC18A (C-Type Lectin Domain Family 18, Member A (CLEC18A))

Alternative Name: CLEC18A

Background: The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-18 (C-type lectin domain family 18) exists as three nearly identical forms, designated CLEC-18A, CLEC-18B and CLEC-18C, or mannose receptor-like protein 1, 2 and 3, respectively. Both CLEC-18A and CLEC-18C contain 446 amino acids, whereas CLEC-18B contains 455 amino acids, all three forms are secreted proteins that contain one C-type lectin domain, a SCP domain and a single EGF-like domain. All three CLEC-18 proteins exist as two alternatively spliced isoforms that are encoded by genes that map to human chromosome 16q22.Synonyms: C-type lectin domain family 18 member A, MRLP2, Mannose receptor-like protein 2

Molecular Weight: 49602 Da

Gene ID: 348174

NCBI Accession: NP_001129686