CysLTR1 antibody (Middle Region)

Catalog No. ABIN951788

The Rabbit Polyclonal anti-CysLTR1 antibody has been validated for WB and EIA. It is suitable to detect CysLTR1 in samples from Human.

Quick Overview for CysLTR1 antibody (Middle Region) (ABIN951788)

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CysLTR1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CysLTR1 Antibody

Binding Specificity: AA 143-172, Middle Region

Specificity: This antibody recognizes Human CYSLTR1 (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of Human CYSLTR1. Genename: CYSLTR1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CysLTR1

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Alternative Name: CYSLTR1

Background: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.Synonyms: CysLTR1, Cysteinyl leukotriene D4 receptor, Cysteinyl leukotriene receptor 1, G-protein coupled receptor HG55, HG55, HMTMF81, LTD4 receptor

Molecular Weight: 38541 Da

Gene ID: 10800

NCBI Accession: NP_006630