DVL2 antibody (C-Term)

Catalog No. ABIN951919

This Rabbit Polyclonal antibody specifically detects DVL2 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for DVL2 antibody (C-Term) (ABIN951919)

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DVL2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-DVL2 Antibody

Binding Specificity: AA 587-617, C-Term

Specificity: This antibody recognizes Human Dishevelled-2 / DVL2 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 587-617 amino acids from the C-terminal region of Human DVL2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DVL2

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Alternative Name: Dishevelled-2 / DVL2

Background: This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.Synonyms: DSH homolog 2, DVL-2, Segment polarity protein dishevelled homolog DVL-2

Molecular Weight: 78948 Da

Gene ID: 1856

NCBI Accession: NP_004413

Pathways: Tube Formation