FGD6
Reactivity: Human
ELISA, WB, IHC
Host: Rabbit
Polyclonal
PE
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
FGD6
(FYVE, RhoGEF and PH Domain Containing 6 (FGD6))
Alternative Name
FGD6
Background
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.Synonyms: FYVE, KIAA1362, RhoGEF and PH domain-containing protein 6, ZFYVE24, Zinc finger FYVE domain-containing protein 24