MGAT3 antibody (C-Term)

Catalog No. ABIN953408

There is 1 publication for this product available. The Rabbit Polyclonal anti-MGAT3 antibody is suitable to detect MGAT3 in samples from Human. It has been validated for WB and EIA.

Quick Overview for MGAT3 antibody (C-Term) (ABIN953408)

Target: MGAT3 (Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase (MGAT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGAT3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MGAT3 Antibody

Binding Specificity: AA 425-454, C-Term

Specificity: This antibody reacts to MGAT3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 425-454 amino acids from the C-terminal region of human MGAT3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-MGAT3 antibody (ABIN953408)

Benson, Grobarova, Richter, Fiserova: "Glycosylation regulates NK cell-mediated effector function through PI3K pathway." in: International immunology, Vol. 22, Issue 3, pp. 167-77, (2010) (PubMed).

Target Details for MGAT3

Target: MGAT3 (Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase (MGAT3))

Alternative Name: MGAT3

Background: There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified.Synonyms: 4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, Beta-1, GGNT3

Molecular Weight: 61313 Da

Gene ID: 4248

NCBI Accession: NP_001091740