NR1D2 antibody (Middle Region)

Catalog No. ABIN953746

This Rabbit Polyclonal antibody specifically detects NR1D2 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for NR1D2 antibody (Middle Region) (ABIN953746)

Target: NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR1D2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-NR1D2 Antibody

Binding Specificity: AA 265-294, Middle Region

Specificity: This antibody reacts to NR1D2.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human NR1D2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NR1D2

Target: NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))

Alternative Name: NR1D2

Background: This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.Synonyms: EAR-1R, Nuclear receptor subfamily 1 group D member 2, Orphan nuclear hormone receptor BD73, Rev-erb-beta

Molecular Weight: 64625 Da

Gene ID: 9975

NCBI Accession: NP_005117

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway