Protocadherin 1 (PCDH1) (N-Term), (AA 186-214) antibody

Details for Product No. ABIN954026
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Antigen
Synonyms PC42, PCDH42, 2010005A06Rik, AI585920, PCDH-1, axpc, protocadherin-1
Epitope
N-Term, AA 186-214
(11), (8), (7), (6), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(50), (17), (17), (14), (14), (13), (1), (1)
Host
Rabbit
(35), (15)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(40), (24), (15), (15), (11), (10), (8), (7), (2), (1), (1)
Pubmed 2 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN954026
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Immunogen KLH conjugated synthetic peptide between 186-214 amino acids from the N-terminal region of human PCDH
Isotype Ig
Specificity This antibody reacts to PCDH1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name PCDH1
Background This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.Synonyms: Cadherin-like protein 1, PC42, Protocadherin 1, Protocadherin 42, Protocadherin-1, Protocadherin-42
Molecular Weight 114743 Da
Gene ID 5097
NCBI Accession NP_002578
Research Area Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Koppelman, Meyers, Howard et al.: "Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness." in: American journal of respiratory and critical care medicine, Vol. 180, Issue 10, pp. 929-35, 2009 (PubMed).

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