PLA2G7 antibody (Middle Region)
Quick Overview for PLA2G7 antibody (Middle Region) (ABIN954165)
Target
See all PLA2G7 (Lp-PLA2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 207-236, Middle Region
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Specificity
- This antibody recognizes PLA2G7.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human
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Purification
- Purified through a Protein A column followed by peptide affinity purification
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 207-236aa) of human PLA2G7.
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
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Alternative Name
- PLA2G7
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Background
- The protein encoded by the PLA2G7 gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency.Synonyms: 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, LDL-PLA2, LDL-associated phospholipase A2, PAF 2-acylhydrolase, PAF acetylhydrolase, PAFAH, Platelet-activating factor acetylhydrolase, gVIIA-PLA2
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Gene ID
- 7941
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NCBI Accession
- NP_001161829
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Pathways
- Peptide Hormone Metabolism
Target
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