PUS1 antibody (C-Term)

Catalog No. ABIN954388

This Rabbit Polyclonal antibody specifically detects PUS1 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for PUS1 antibody (C-Term) (ABIN954388)

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PUS1 Antibody

Binding Specificity: AA 329-358, C-Term

Specificity: This antibody recognizes Humann PUS1 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of Human PUS1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PUS1

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Alternative Name: PUS1

Background: This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variantsSynonyms: MGC11268, MLASA1, PP8985, Pseudouridylate synthase 1, tRNA pseudouridine synthase A mitochondrial, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I

Molecular Weight: 47470 Da

Gene ID: 80324

NCBI Accession: NP_001002019