RCBTB1
Reactivity: Rat
ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
RCBTB1
(Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 (RCBTB1))
Alternative Name
RCBTB1
Background
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.Synonyms: CLL deletion region gene 7 protein, CLLD7, Chronic lymphocytic leukemia deletion region gene 7 protein, RCC1 and BTB domain-containing protein 1, Regulator of chromosome condensation and BTB domain-containing protein 1