Retinoid X Receptor beta antibody (Middle Region)
Quick Overview for Retinoid X Receptor beta antibody (Middle Region) (ABIN954648)
Target
See all Retinoid X Receptor beta (RXRB) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 262-292, Middle Region
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Specificity
- Recognizes RXRB (Center).
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Purification
- Protein A column followed by peptide Affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 262~292 amino acids from the Central region of Human RXRB Genename: RXRB
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))
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Alternative Name
- RXR-beta / RXRB
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Background
- This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.Synonyms: H-2RIIBP, NR2B2, Nuclear Receptor Coregulator 1, Nuclear receptor subfamily 2 group B member 2, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta
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Gene ID
- 6257
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NCBI Accession
- NP_068811
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Target
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