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Six5 (AA 264-294), (Middle Region) antibody

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Synonyms Dmahp, MDMAHP, TrexBF, BOR2, DMAHP
AA 264-294, Middle Region
(16), (15), (11), (2), (1), (1)
(28), (8)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(27), (22), (16), (3), (2), (1)
Pubmed 4 references available
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Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 264-294 amino acids from the Central region of Human SIX5. Genename: SIX5
Isotype Ig
Specificity This antibody recognizes Human SIX5 (Center).
Purification Protein A column, followed by peptide affinity purification
Background The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2.Synonyms: DM locus-associated homeodomain protein, DMAHP, Homeobox protein SIX5, Sine oculis homeobox homolog 5
Molecular Weight 74562 Da
Gene ID 147912
NCBI Accession NP_787071
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Six5 (AA 264-294), (Middle Region) antibody (ABIN954812) Formalin fixed, paraffin embedded human liver tissue stained with SIX5 Antibody  foll...
Western Blotting (WB) image for anti-Six5 (AA 264-294), (Middle Region) antibody (ABIN954812) Western blot analysis of SIX5 Antibody  in MDA-MB231 cell line lysates (35ug/lane). T...
Background publications Yoshida, Kato, Yokoi et al.: "Association of genetic variants with hemorrhagic stroke in Japanese individuals." in: International journal of molecular medicine, Vol. 25, Issue 4, pp. 649-56, 2010 (PubMed).

Oguri, Kato, Yokoi et al.: "Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals." in: American journal of hypertension, Vol. 23, Issue 1, pp. 70-7, 2009 (PubMed).

Hoskins, Cramer, Silvius et al.: "Transcription factor SIX5 is mutated in patients with branchio-oto-renal syndrome." in: American journal of human genetics, Vol. 80, Issue 4, pp. 800-4, 2007 (PubMed).

Sato, Nakamura, Cho et al.: "Identification of transcriptional targets for Six5: implication for the pathogenesis of myotonic dystrophy type 1." in: Human molecular genetics, Vol. 11, Issue 9, pp. 1045-58, 2002 (PubMed).

Catalog No. ABIN954812
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