Six5 (AA 264-294), (Middle Region) antibody

Details for Product No. ABIN954812
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Antigen
Synonyms Dmahp, MDMAHP, TrexBF, BOR2, DMAHP
Epitope
AA 264-294, Middle Region
(9), (7), (2), (1), (1), (1)
Reactivity
Human
(20), (10)
Host
Rabbit
(21)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(21), (15), (8), (3), (1)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN954812
357.50 $
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Immunogen KLH conjugated synthetic peptide between 264-294 amino acids from the Central region of Human SIX5. Genename: SIX5
Isotype Ig
Specificity This antibody recognizes Human SIX5 (Center).
Purification Protein A column, followed by peptide affinity purification
Background The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2.Synonyms: DM locus-associated homeodomain protein, DMAHP, Homeobox protein SIX5, Sine oculis homeobox homolog 5
Molecular Weight 74562 Da
Gene ID 147912
NCBI Accession NP_787071
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Sato, Nakamura, Cho et al.: "Identification of transcriptional targets for Six5: implication for the pathogenesis of myotonic dystrophy type 1." in: Human molecular genetics, Vol. 11, Issue 9, pp. 1045-58, 2002 (PubMed).

Hoskins, Cramer, Silvius et al.: "Transcription factor SIX5 is mutated in patients with branchio-oto-renal syndrome." in: American journal of human genetics, Vol. 80, Issue 4, pp. 800-4, 2007 (PubMed).

Oguri, Kato, Yokoi et al.: "Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals." in: American journal of hypertension, Vol. 23, Issue 1, pp. 70-7, 2009 (PubMed).

Yoshida, Kato, Yokoi et al.: "Association of genetic variants with hemorrhagic stroke in Japanese individuals." in: International journal of molecular medicine, Vol. 25, Issue 4, pp. 649-56, 2010 (PubMed).

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