ULK1 antibody

Catalog No. ABIN955448

The Rabbit Polyclonal anti-ULK1 antibody has been validated for WB, FACS, IHC (p) and EIA. It is suitable to detect ULK1 in samples from Human and Mouse.

Quick Overview for ULK1 antibody (ABIN955448)

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ULK1 Antibody

Specificity: This antibody recognizes Human and Mouse Unc-51-like kinase 1 (ULK1).

Purification: Affinity Chromatography on Proteinn A

Immunogen: KLH conjugated synthetic peptide selected from Human Unc-51-like kinase 1 (ULK1) Genename: ULK1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Alternative Name: Unc-51-Like Kinase 1 (ULK1)

Background: ULK1 is involved in autophagy. It is required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. It is involved in axon growth (By similarity) and plays an essential role in neurite extension of cerebellar granule cells (By similarity).Synonyms: KIAA0722, Serine/threonine-protein kinase ULK1

Molecular Weight: 112601 Da

Gene ID: 8408

NCBI Accession: NP_003556

Pathways: Regulation of Cell Size, Autophagy