Apolipoprotein M antibody

Catalog No. ABIN965579

There are 3+ publications for this product available. The Monoclonal anti-Apolipoprotein M antibody is suitable to detect Apolipoprotein M in samples from Human. It has been validated for WB, ELISA and IF.

Quick Overview for Apolipoprotein M antibody (ABIN965579)

Target: Apolipoprotein M (APOM)

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This Apolipoprotein M antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Apolipoprotein M Antibody

Specificity: Ni-NTA purified full-length recombinant ApoM.trx expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1, IgG2b

Application Details

Application Notes: Western Blot: 1: 500- 1: 2,000
IF: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

References for anti-Apolipoprotein M antibody (ABIN965579)

Zhang, Jiao, Hurtig, Dong, Zheng, Luo, Nilsson-Ehle, Ye, Xu: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." in: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, (2004) (PubMed).

Duan, Dahlbäck, Villoutreix: "Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis." in: FEBS letters, Vol. 499, Issue 1-2, pp. 127-32, (2001) (PubMed).

Xu, Dahlbäck: "A novel human apolipoprotein (apoM)." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31286-90, (1999) (PubMed).

Target Details for Apolipoprotein M

Target: Apolipoprotein M (APOM)

Alternative Name: ApoM

Background: ApoM(apolipoprotein M,also designated G3a or NG20),with 188-amino acid protein(about 21kDa),is an apolipoprotein and member of the lipocalin protein family. The Apo-proteins are involved in the specific binding of cellular receptors, the regulation of lipolytic enzymes, and the process of lipid exchange. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro,Apo-M is glycosylated when translated in the presence of microsomes, and remains associated with the microsomes after carbonate treatment.Apo-M is expressed in liver and kidney, and is secreted into the bloodstream in HDLs,and also found in triglyceride-rich lipoproteins and LDLs.

Gene ID: 55937