AQP2 antibody (N-Term)

Catalog No. ABIN965586

This anti-AQP2 antibody is a Rabbit Polyclonal antibody detecting AQP2 in WB and ELISA. Suitable for Human.

Quick Overview for AQP2 antibody (N-Term) (ABIN965586)

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AQP2 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human AQP2(aquaporin 2)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for AQP2

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Alternative Name: AQP2

Background: The AQP2(aquaporin 2)is a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. In collecting duct cells, AQP2 trafficking to vasopressin-sensitive vesicles is phosphorylation-independent and phosphorylation of Ser-256 is necessary for expression of AQP2 in the apical membrane. The changes in urinary excretion of aquaporin-2 indicates circulatory blood volume depletion, and estimates the AVP-dependent recovery of circulatory blood volume during the therapeutic period in patients with diabetic ketoacidosis

Pathways: Response to Water Deprivation