BTG1 antibody (N-Term)

Catalog No. ABIN965706

This anti-BTG1 antibody is a Rabbit Polyclonal antibody detecting BTG1 in IHC. Suitable for Human, Mouse, Rat and Chicken.

Quick Overview for BTG1 antibody (N-Term) (ABIN965706)

Target: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTG1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-BTG1 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human BTG1(B-cell translocation gene 1 protein)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for BTG1

Target: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Alternative Name: BTG1

Background: BTG1(B-cell translocation gene 1 protein) is an anti-proliferative protein. Its expression is associated with the early G1 phase of the cell cycle. A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. BTG1 expression is maximal in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. GTG1 negatively regulates cell proliferation. BTG1 is a novel important coactivator involved in the regulation of myoblast differentiation. BTG1 may play an important role in the process of angiogenesis. Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system. The C-terminal regions are necessary and sufficient to control the stabilities of BTG1, BTG2, Tob, and Tob2 proteins.

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development