CAMP Responsive Element Binding Protein 1 (CREB1) antibody

Details for Product No. ABIN965926
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Antigen
Synonyms creb, CREB1, Creb1, CREB, 2310001E10Rik, 3526402H21Rik, AV083133, Creb, Creb-1, creb1, zgc:55598
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(473), (239), (237), (13), (11), (9), (8), (8), (6), (6), (4), (2), (2), (1)
Host
Rabbit
(414), (67), (10), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(15), (14), (13), (7), (7), (6), (6), (5), (4), (4), (4), (4), (4), (4)
Application
Immunohistochemistry (IHC)
(388), (220), (195), (64), (62), (42), (36), (26), (23), (11), (7), (5), (3), (3), (2), (2), (2), (2), (1), (1)
Pubmed 3 references available
Quantity 100 μg
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 (I-L-SP-R-R).
Specificity CREB (Ab-129) antibody detects endogenous levels of total CREB protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name CREB (CREB1 Antibody Abstract)
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Garat, Fankell, Erickson et al.: "Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 4934-48, 2006 (PubMed).

Rothem, Stark, Assaraf: "Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene." in: Molecular pharmacology, Vol. 66, Issue 6, pp. 1536-43, 2004 (PubMed).

Tyson, Swarthout, Jefcoat et al.: "PTH induction of transcriptional activity of the cAMP response element-binding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites." in: Endocrinology, Vol. 143, Issue 2, pp. 674-82, 2002 (PubMed).

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Catalog No. ABIN965926
398.75 $
Plus shipping costs $45.00
Quantity
Price
100 μg
398.75 $

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