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CREB1 antibody (CAMP Responsive Element Binding Protein 1)

Details for Product anti-CREB1 Antibody No. ABIN965926, Supplier: Login to see
Antigen
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
Alternatives
anti-Human CREB1 antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
468
223
219
23
21
16
14
13
9
8
8
6
5
2
2
1
Host
Rabbit
404
70
10
1
Clonality
Polyclonal
Conjugate
This CREB1 antibody is un-conjugated
15
14
13
7
6
6
6
5
4
3
3
3
3
3
3
Application
Immunohistochemistry (IHC)
368
215
183
64
62
39
34
29
25
11
7
3
3
2
2
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 (I-L-SP-R-R).
Specificity CREB (Ab-129) antibody detects endogenous levels of total CREB protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name CREB (CREB1 Antibody Abstract)
Pathways TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Garat, Fankell, Erickson et al.: "Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 4934-48, 2006 (PubMed).

Rothem, Stark, Assaraf: "Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene." in: Molecular pharmacology, Vol. 66, Issue 6, pp. 1536-43, 2004 (PubMed).

Tyson, Swarthout, Jefcoat et al.: "PTH induction of transcriptional activity of the cAMP response element-binding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites." in: Endocrinology, Vol. 143, Issue 2, pp. 674-82, 2002 (PubMed).