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Details for Product No. ABIN966031

Epidermal Growth Factor (EGF) antibody

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Antigen
Synonyms CEGF, URG, HOMG4, AI790464
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Pubmed 4 references available
Catalog no. ABIN966031
Quantity 0.1 mL
Price
426.25 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen Purified recombinant fragment of human EGF expressed in E. Coli.
Clone 4E11
Isotype IgG1
Purification Ascitic fluid
Alternative Name EGF
Background Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide.
Synonyms: URG, HOMG4, EGF
Molecular Weight 134kDa
Gene ID 1950
Research Area Cancer, Growth Factors
Application Notes Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Preservative Sodium azide
Storage 4 °C
Product cited in: Gout, Dhand, Panayotou et al.: "Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system." in: The Biochemical journal, Vol. 288 ( Pt 2), pp. 395-405, 1993 (PubMed).

Gual, Giordano, Williams et al.: "Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis." in: Oncogene, Vol. 19, Issue 12, pp. 1509-18, 2000 (PubMed).

Soubeyran, Kowanetz, Szymkiewicz et al.: "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors." in: Nature, Vol. 416, Issue 6877, pp. 183-7, 2002 (PubMed).

Yacoub, McKinstry, Hinman et al.: "Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling." in: Radiation research, Vol. 159, Issue 4, pp. 439-52, 2003 (PubMed).

Alternatives for antigen "Epidermal Growth Factor (EGF)", type "Antibodies"
Hosts (181), (109), (18), (4), (4), (1)
Reactivities (186), (98), (65), (6), (6), (4), (4), (1), (1), (1)
Applications (194), (174), (62), (60), (46), (31), (23), (15), (11), (10), (9), (9), (7), (6), (5), (4), (3), (2), (2), (2)
Conjugates (36), (11), (9), (6), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (4), (4)
Epitopes (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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