EPH Receptor A8 antibody (AA 70-150)

Catalog No. ABIN966074

There is 1 publication for this product available. The Mouse Monoclonal anti-EPH Receptor A8 antibody is suitable to detect EPH Receptor A8 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for EPH Receptor A8 antibody (AA 70-150) (ABIN966074)

Target: EPH Receptor A8 (EPHA8)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor A8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 9A12D8

Product Details anti-EPH Receptor A8 Antibody

Binding Specificity: AA 70-150

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of EphA8 (aa70-150) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-EPH Receptor A8 antibody (ABIN966074)

Yamaguchi, Pasquale: "Eph receptors in the adult brain." in: Current opinion in neurobiology, Vol. 14, Issue 3, pp. 288-96, (2004) (PubMed).

Target Details for EPH Receptor A8

Target: EPH Receptor A8 (EPHA8)

Alternative Name: EphA8

Background: EphA8: EPH receptor A8. This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
Synonyms: EEK, HEK3, KIAA1459, EPHA8

Gene ID: 2046

Pathways: RTK Signaling