GNB4 antibody (N-Term)

Catalog No. ABIN966216

Product Details anti-GNB4 Antibody

Target: GNB4 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 4 (GNB4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human GNB4 (Guanine nucleotide-binding protein beta subunit 4)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-GNB4 antibody (ABIN966216)

Rosskopf, Nikula, Manthey, Joisten, Frey, Kohnen, Siffert: "The human G protein beta4 subunit: gene structure, expression, Ggamma and effector interaction." in: FEBS letters, Vol. 544, Issue 1-3, pp. 27-32, (2003) (PubMed).

Ruiz, de la Rubia, Pérez, Martínez Lopez: "Effect of olive oil mill wastewater on extracellular ligninolytic enzymes produced by Phanerochaete flavido-alba." in: FEMS microbiology letters, Vol. 212, Issue 1, pp. 41-5, (2002) (PubMed).

Target Details for GNB4

Target: GNB4 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 4 (GNB4))

Alternative Name: GNB4 (GNB4 Products)

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNB4(Guanine nucleotide-binding protein beta subunit 4) is a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. GNB4 is involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G proteineffector interaction.

Pathways: Myometrial Relaxation and Contraction