HSF1 antibody

Catalog No. ABIN966306

Cited in 4+ publications. The Rabbit Polyclonal anti-HSF1 antibody (ABIN966306) specifically detects HSF1 in IHC. The antibody is reactive with Human samples.

Quick Overview for HSF1 antibody (ABIN966306)

Target: HSF1 (Heat Shock Factor Protein 1 (HSF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-HSF1 Antibody

Specificity: HSF1 (Ab-303) antibody detects endogenous levels of total HSF1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human HSF1 around the phosphorylation site of serine 303 (P-P-SP-P-P).

Application Details

Application Notes: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-HSF1 antibody (ABIN966306)

Rafiee, Theriot, Nelson, Heidemann, Kanaa, Horowitz, Rogaczewski, Johnson, Ali, Shaker, Binion: "Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27." in: American journal of physiology. Cell physiology, Vol. 291, Issue 5, pp. C931-45, (2006) (PubMed).

Takaki, Fujimoto, Sugahara, Nakahari, Yonemura, Tanaka, Hayashida, Inouye, Takemoto, Yamashita, Nakai: "Maintenance of olfactory neurogenesis requires HSF1, a major heat shock transcription factor in mice." in: The Journal of biological chemistry, Vol. 281, Issue 8, pp. 4931-7, (2006) (PubMed).

Shinozaki, Minami, Chiba, Suzuki, Yoshimatsu, Ichikawa, Terasawa, Emori, Matsumoto, Kurosaki, Nakai, Tanaka, Minami: "Depletion of hsp90beta induces multiple defects in B cell receptor signaling." in: The Journal of biological chemistry, Vol. 281, Issue 24, pp. 16361-9, (2006) (PubMed).

Hung, Cheng, Lai, Chang: "Differential activation of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinases confers cadmium-induced HSP70 expression in 9L rat brain tumor cells." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31924-31, (1998) (PubMed).

Target Details for HSF1

Target: HSF1 (Heat Shock Factor Protein 1 (HSF1))

Alternative Name: HSF1