The Rabbit Polyclonal anti-HspX antibody has been validated for IHC. It is suitable to detect HspX in samples from Mycobacterium tuberculosis. There are 2+ publications available.
Quick Overview for HspX antibody (N-Term) (ABIN966323)
Target
HspX (HSPX)
(Heat Shock Protein HspX (HSPX))
Reactivity
Mycobacterium tuberculosis
Host
Rabbit
Clonality
Polyclonal
Conjugate
This HspX antibody is un-conjugated
Application
Immunohistochemistry (IHC)
Binding Specificity
N-Term
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Bacteria Mycobacterium tuberculosis HSPX (heat shock protein hspX)
Garnier, Eiglmeier, Camus, Medina, Mansoor, Pryor, Duthoy, Grondin, Lacroix, Monsempe, Simon, Harris, Atkin, Doggett, Mayes, Keating, Wheeler, Parkhill, Barrell, Cole, Gordon, Hewinson: "The complete genome sequence of Mycobacterium bovis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 13, pp. 7877-82, (2003) (PubMed).
Cole, Brosch, Parkhill, Garnier, Churcher, Harris, Gordon, Eiglmeier, Gas, Barry, Tekaia, Badcock, Basham, Brown, Chillingworth, Connor, Davies, Devlin, Feltwell, Gentles, Hamlin, Holroyd, Hornsby et al.: "Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. ..." in: Nature, Vol. 393, Issue 6685, pp. 537-44, (1998) (PubMed).
Target
HspX (HSPX)
(Heat Shock Protein HspX (HSPX))
Alternative Name
HSPX
Background
HSPX (heat shock protein hspX) functions as stress protein induced by anoxia. hspX has a proposed role in maintenance of long-term viability during latent, asymptomatic infections, and a proposed role in replication during initial infection. regulated by the two component regulatory system devr|rv3133c/devs|rv3132c, in response to a hypoxic signal. The hspX contains a ACD_sHsps-like domain. Alpha-crystallin domain (ACD) of alpha-crystallin- type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD).