conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody

Details for Product No. ABIN966383
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Antigen
Synonyms ikk, ikk1, ikka, ikkalpha, CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16, AI256658, Chuk1, Fbx24, Fbxo24, Ikka, zgc:56539
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(271), (101), (94), (48), (24), (24), (24), (12), (1)
Host
Rabbit
(229), (45), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(10), (8), (8), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Application
Immunohistochemistry (IHC)
(232), (114), (61), (48), (43), (40), (34), (28), (8), (3), (2), (1), (1)
Pubmed 2 references available
Quantity 100 μg
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Catalog No. ABIN966383
398.75 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IKK around the phosphorylation site of Threonine 23 (L-G-TP-G-G).
Specificity IKK (Ab-23) Antibody detects endogenous levels of total IKK protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name IKK alpha
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Ozes, Mayo, Gustin et al.: "NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase." in: Nature, Vol. 401, Issue 6748, pp. 82-5, 1999 (PubMed).

Yuan, Feldman, Sun et al.: "Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29973-82, 2002 (PubMed).

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