anti-CHUK antibody (conserved Helix-Loop-Helix Ubiquitous Kinase)

Details for Product anti-CHUK Antibody No. ABIN966383
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Synonyms ikk, ikk1, ikka, ikkalpha, CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16, AI256658, Chuk1, Fbx24, Fbxo24, Ikka, zgc:56539
Human, Mouse (Murine), Rat (Rattus)
(339), (109), (81), (2), (2), (1)
(287), (55), (10), (2)
This CHUK antibody is un-conjugated
(14), (10), (10), (8), (8), (8), (2), (2), (2), (2), (2), (2), (2), (2)
Immunohistochemistry (IHC)
(312), (141), (101), (45), (41), (40), (34), (20), (10), (9), (9), (3), (3), (2), (1), (1)
Pubmed 2 references available
Quantity 100 μg
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IKK around the phosphorylation site of Threonine 23 (L-G-TP-G-G).
Specificity IKK (Ab-23) Antibody detects endogenous levels of total IKK protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name IKK alpha (CHUK Antibody Abstract)
Pathways PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Yuan, Feldman, Sun et al.: "Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29973-82, 2002 (PubMed).

Ozes, Mayo, Gustin et al.: "NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase." in: Nature, Vol. 401, Issue 6748, pp. 82-5, 1999 (PubMed).

Catalog No. ABIN966383
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