IKK alpha Products
(conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
Categories
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008].
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Featured IKK alpha Categories
IKK alpha Antibodies
High quality antibodies with extensive validation data.
IKK alpha ELISA Kits
Reliable ELISA kits for a wide range of species.
IKK alpha Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IKK alpha Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (3)
- (9)
Cat. No.
ABIN3022825
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (6)
Cat. No.
ABIN6256173
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN560378
Quantity
100 μg
Datasheet
Datasheet
Recommended IKK alpha ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955060
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999499
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380611
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended IKK alpha Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570632
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349452
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3093092
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our IKK alpha products
: "Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations." in: Oncogene, Vol. 40, Issue 2, pp. 355-368, (2021) (PubMed).: "NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice." in: Gastroenterology, Vol. 156, Issue 4, pp. 1156-1172.e6, (2019) (PubMed).
: "IKKα Promotes the Progression and Metastasis of Non-Small Cell Lung Cancer Independently of its Subcellular Localization." in: Computational and structural biotechnology journal, Vol. 17, pp. 251-262, (2019) (PubMed).
: "IKKα deficiency disrupts the development of marginal zone and follicular B cells." in: Genes and immunity, (2018) (PubMed).
: "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018) (PubMed).
: "IKKα controls ATG16L1 degradation to prevent ER stress during inflammation." in: The Journal of experimental medicine, Vol. 214, Issue 2, pp. 423-437, (2017) (PubMed).
: "Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis." in: Cell host & microbe, Vol. 21, Issue 4, pp. 478-493.e7, (2017) (PubMed).
: "Novel chemiluminescent Western blot blocking and antibody incubation solution for enhanced antibody-antigen interaction and increased specificity." in: Electrophoresis, Vol. 38, Issue 20, pp. 2631-2637, (2017) (PubMed).
: "Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas." in: Cancer cell, Vol. 32, Issue 6, pp. 824-839.e8, (2017) (PubMed).
: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).
Synonyms and alternative names related to IKK alpha
conserved helix-loop-helix ubiquitous kinase S homeolog (chuk.S), conserved helix-loop-helix ubiquitous kinase (CHUK), conserved helix-loop-helix ubiquitous kinase (Chuk), conserved helix-loop-helix ubiquitous kinase (chuk), AI256658, CHUK, Chuk1, Fbx24, Fbxo24, IKBKA, ikk, IKK-alpha, ikk1, IKK1, ikka, IKKA, Ikka, ikkalpha, NFKBIKA, TCF16, zgc:56539Protein level used designations for IKK alpha
- IKK-A
- IKK-alpha
- NFKBIKA
- i kappa-B kinase alpha
- ikBKA
- inhibitor of nuclear factor kappa-B kinase subunit alpha
- nuclear factor NF-kappa-B inhibitor kinase alpha
- SPFH domain-containing protein 1
- conserved helix-loop-helix ubiquitous kinase
- I-kappa-B kinase 1
- I-kappa-B kinase-alpha
- IKK-a kinase
- IkB kinase alpha subunit
- Nuclear factor NFkappaB inhibitor kinase alpha
- TCF-16
- transcription factor 16
- I kappa B kinase 1
- I-kappa-B kinase alpha
- IKK alpha
- IkappaB kinase alpha
- ikappaB kinase
- IkB kinase-a
- IKK1
- IKKa
- pky
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