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Interleukin 8 antibody (IL8)

Details for Product anti-IL8 Antibody No. ABIN966396, Supplier: Log in to see
Antigen
  • IL8
  • K60
  • interleukin-8
  • il8
  • si:dkey-151b16.2
  • cxcli2
  • Il8
  • Scyb15
  • lungkine
  • weche
  • CXCL8
  • GCP-1
  • GCP1
  • LECT
  • LUCT
  • LYNAP
  • MDNCF
  • MONAP
  • NAF
  • NAP-1
  • NAP1
  • IL-8
  • AMCF-I
  • EMF-1
Reactivity
Human
357
30
26
20
16
14
12
8
8
6
4
4
4
4
3
1
1
1
1
1
Host
247
218
9
7
7
4
2
Clonality
Monoclonal
Conjugate
This Interleukin 8 antibody is un-conjugated
58
46
15
6
4
3
2
2
2
2
2
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
320
291
83
60
36
29
26
24
23
22
16
14
12
6
5
5
4
3
2
2
2
2
1
1
1
1
1
1
Supplier
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Isotype IgG1 kappa
Specificity Ni-NTA purified recombinant human IL-8 expressed in E.Coli. strain BL21 (DE3).
Purification Antibodies are purified by protein A affinity chromatography
Alternative Name IL-8 (IL8 Antibody Abstract)
Background Interleukin-8 (IL-8)is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
Gene ID 3576
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Pathways
Application Notes Dilution: Western Blot: 1:500-1,000
ELISA: 1,000-2,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Storage -20 °C
Product cited in: Mukaida, Shiroo, Matsushima: "Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 143, Issue 4, pp. 1366-71, 1989 (PubMed).

Baggiolini, Clark-Lewis: "Interleukin-8, a chemotactic and inflammatory cytokine." in: FEBS letters, Vol. 307, Issue 1, pp. 97-101, 1992 (PubMed).