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Interleukin 8 (IL8) antibody

Antigen

Interleukin 8 (IL8)

Synonyms NAF, GCP1, LECT, LUCT, NAP1, CXCL8, GCP-1, LYNAP, MDNCF, MONAP, NAP-1, IL-8, IL8, K60, EMF-1, AMCF-I, il8, si:dkey-151b16.2, cxcli2
Clonality Monoclonal
Host
Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Catalog no. ABIN966396
Quantity 0.1mg
Price 288.75 $   Plus shipping costs $45.00
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Additional Information

Alternative name IL-8
Gene ID 3576
Isotype IgG1 kappa
Description Interleukin-8 (IL-8)is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
Specificity Ni-NTA purified recombinant human IL-8 expressed in E.Coli. strain BL21 (DE3).

Application Details

Application Notes Dilution: Western Blot: 1:500-1,000
ELISA: 1,000-2,000.
Determining optimal working dilutions by titration test.
Purification Antibodies are purified by protein A affinity chromatography
Storage Store at -20° C.
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Restrictions For Research Use only

Publications

Product Baggiolini, Clark-Lewis: "Interleukin-8, a chemotactic and inflammatory cytokine." in: FEBS letters, Vol. 307, Issue 1, pp. 97-101, 1992 (PubMed).

Mukaida, Shiroo, Matsushima: "Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 143, Issue 4, pp. 1366-71, 1989 (PubMed).

Alternatives

Alternatives for antigen "Interleukin 8 (IL8)", type "Antibodies"
Hosts Rabbit (121), Mouse (102), Guinea Pig (5), Chicken (4), Goat (4), Rat (3), Sheep (2)
Reactivities Human (171), Sheep (Ovine) (26), Dog (Canine) (24), Pig (Porcine) (24), Cow (Bovine) (21), Mouse (Murine) (20), Rat (Rattus) (20), Cat (Feline) (7), Rabbit (6), Guinea Pig (4), Chicken (3), Horse (Equine) (3), Wild boar (Sus scrofa) (3), Rhesus Monkey (2), Monkey (1)
Applications ELISA (160), Western Blotting (WB) (148), Immunohistochemistry (IHC) (62), Immunofluorescence (IF) (40), Flow Cytometry (FACS) (15), Functional Studies (Func) (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Immunoprecipitation (IP) (13), Immunocytochemistry (ICC) (11), Neutralization (Neut) (11), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (5), Dot Blot (Dot) (4), Immunoassay (IA) (4), Immunohistochemistry (Fixed) (IHC (fx)) (3), Intracellular Staining (IS) (3), Blocking Antibody (Inhibition) (2), Cellular Assay (CA) (2), Enzyme Immunoassay (EIA) (2), Immunoelectron Microscopy (IEM) (2), Immunostaining (ISt) (2), Radioimmunoassay (RIA) (2), Blocking Antibody (Inhibition) (1), Fluorescence Microscopy (FM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Transfected cell culture (TCC) (1)
Conjugates Biotin (26), FITC (16), HRP (4), PE (4), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
Epitopes AA 23-101 (4), Internal Region (3), N-Term (3), AA 28-99 (2), C-Term (1), C-Term,AA 77-95 (1)