SLC16A1 antibody (N-Term)

Catalog No. ABIN966547

This Rabbit Polyclonal antibody specifically detects SLC16A1 in IHC. It exhibits reactivity toward Rat and Mouse and has been mentioned in 2+ publications.

Quick Overview for SLC16A1 antibody (N-Term) (ABIN966547)

Target: SLC16A1 (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC16A1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SLC16A1 Antibody

Binding Specificity: N-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Mct1 (Monocarboxylate transporter 1)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-SLC16A1 antibody (ABIN966547)

Koehler-Stec, Simpson, Vannucci, Landschulz, Landschulz: "Monocarboxylate transporter expression in mouse brain." in: The American journal of physiology, Vol. 275, Issue 3 Pt 1, pp. E516-24, (1998) (PubMed).

Carpenter, Poole, Halestrap: "Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function." in: Biochimica et biophysica acta, Vol. 1279, Issue 2, pp. 157-63, (1996) (PubMed).

Target Details for SLC16A1

Target: SLC16A1 (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1))

Alternative Name: Mct1

Background: Mct1 (Monocarboxylate transporter 1) functions as a Proton-linked monocarboxylate transporter. Mct1 (Monocarboxylate transporter 1) catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Mct1 (Monocarboxylate transporter 1) is a multi-pass membrane protein. Major isoform present in tumor cells, erythrocytes. Mct1 belongs to the major facilitator superfamily and Monocarboxylate porter (TC 2.A.1.13) family.
Synonyms: Slc16a1 (Solute carrier family 16 member 1)

Pathways: Warburg Effect