MMP10 antibody (C-Term)

Catalog No. ABIN966586

This Polyclonal antibody specifically detects MMP10 in WB. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for MMP10 antibody (C-Term) (ABIN966586)

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivity: Human

Host: Please inquire

Clonality: Polyclonal

Conjugate: This MMP10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP10 Antibody

Binding Specificity: AA 410-422, C-Term

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human MMP-10 (410-422 aa), identical to the related mouse and rat sequence.

Application Details

Application Notes: WB: The detection limit for MMP-10 is approximately 2.5ng/lane under non-reducing and reducing conditions.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Preservative: Thimerosal (Merthiolate), Sodium azide

Storage: -20 °C

References for anti-MMP10 antibody (ABIN966586)

Jung, Warter, Rumpler: "Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization." in: Annales de génétique, Vol. 33, Issue 1, pp. 21-3, (1990) (PubMed).

Muller, Quantin, Gesnel, Millon-Collard, Abecassis, Breathnach: "The collagenase gene family in humans consists of at least four members." in: The Biochemical journal, Vol. 253, Issue 1, pp. 187-92, (1988) (PubMed).

Target Details for MMP10

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Alternative Name: MMP-10

Background: Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.