Orthodenticle Homeobox 2 (OTX2) antibody

Details for Product No. ABIN966720
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Antigen
Synonyms CPHD6, MCOPS5, Xotx-2, Xotx2, otx-2, otx2, id:ibd2915, zOtx2, zgc:136535, zotx-2, E130306E05Rik
Reactivity
Human
(57), (19), (18), (15), (15), (15), (3), (2), (2), (1), (1)
Host
Mouse
(43), (15), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA
(49), (28), (24), (13), (10), (8), (8), (4), (2), (1)
Pubmed 2 references available
Quantity 0.1 mL
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Catalog No. ABIN966720
481.25 $
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Immunogen Purified recombinant fragment of human OTX2 expressed in E. Coli.
Clone 1H12C4B5
Isotype IgG1
Purification Ascitic fluid
Alternative Name OTX2
Background This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development.
Tissue specificity: Expressed in brain.
Synonyms: MCOPS5, MGC45000
Molecular Weight 32kDa
Gene ID 5015
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Wyatt, Bakrania, Bunyan et al.: "Novel heterozygous OTX2 mutations and whole gene deletions in anophthalmia, microphthalmia and coloboma." in: Human mutation, Vol. 29, Issue 11, pp. E278-83, 2008 (PubMed).

Adamson, Shi, Wortham et al.: "OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas." in: Cancer research, Vol. 70, Issue 1, pp. 181-91, 2010 (PubMed).

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