P21-Activated Kinases 1/2/3 (PAK1/2/3) antibody

Details for Product No. ABIN966799
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Antigen
Synonyms X-PAK1, XPak1, pak, pak-1, pakalpha
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(49), (33), (30), (14), (14)
Host
Rabbit
(52)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(19), (17), (15), (15), (13), (10), (4), (3)
Pubmed 3 references available
Catalog no. ABIN966799
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human PAK1around the phosphorylation site of threonine 423 (R-S-TP-M-V).
Specificity PAK1/PAK2/PAK3 (Ab-423/402/421) antibody detects endogenous levels of total PAK1/PAK2/PAK3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name PAK1/PAK2/PAK3
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Lampugnani, Zanetti, Breviario et al.: "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam." in: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1175-89, 2002 (PubMed).

Wang, Mazumdar, Vadlamudi et al.: "P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium." in: The EMBO journal, Vol. 21, Issue 20, pp. 5437-47, 2002 (PubMed).

Parsons, Monypenny, Ameer-Beg et al.: "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1680-95, 2005 (PubMed).

Hosts (52)
Reactivities (49), (33), (30), (14), (14)
Applications (19), (17), (15), (15), (13), (10), (4), (3)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (20), (16), (13), (11), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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