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P21-Activated Kinases 1/2/3 (PAK1/2/3) antibody

Antigen

P21-Activated Kinases 1/2/3 (PAK1/2/3)
Synonyms PAKalpha, MGC130000, MGC130001, Paka, PAK-1, AW045634, PAK1, MGC83445, MGC139676
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Application
Alternatives Immunohistochemistry (IHC)
3 references available
Catalog no. ABIN966799
Quantity 100ug  (100ug/100ul.)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name PAK1/PAK2/PAK3
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human PAK1around the phosphorylation site of threonine 423 (R-S-TP-M-V).
Specificity PAK1/PAK2/PAK3 (Ab-423/402/421) antibody detects endogenous levels of total PAK1/PAK2/PAK3 protein.

Application Details
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Application Notes IHC: 1:50-1:100.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Lampugnani, Zanetti, Breviario et al.: "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam." in: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1175-89, 2002 (PubMed).

Wang, Mazumdar, Vadlamudi et al.: "P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium." in: The EMBO journal, Vol. 21, Issue 20, pp. 5437-47, 2002 (PubMed).

Parsons, Monypenny, Ameer-Beg et al.: "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1680-95, 2005 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "P21-Activated Kinases 1/2/3 (PAK1/2/3)", type "Antibodies"
Hosts Rabbit (23)
Reactivities Human (23), Mouse (Murine) (15), Rat (Rattus) (15)
Applications Immunohistochemistry (IHC) (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunofluorescence (IF) (8), ELISA (5), Immunocytochemistry (ICC) (4), Immunoprecipitation (IP) (2), Western Blotting (WB) (2)
Epitopes pThr402, pThr421, pThr423 (6), pThr423,pThr402,pThr421 (3), Thr402, Thr421, Thr423 (2), Thr423,Thr402,Thr421 (2), Internal Region (1), pThr423 (1)