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PAK1/2/3 antibody
PAK1/2/3
Reactivity: Human, Rat, Mouse
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PAK1/2/3 Antibody
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Target
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PAK1/2/3
(P21-Activated Kinases 1/2/3 (PAK1/2/3))
Reactivity
All reactivities for PAK1/2/3 antibodies
Human, Rat, Mouse
Host
All hosts for PAK1/2/3 antibodies
Rabbit
Clonality
All clonalities for PAK1/2/3 antibodies
Polyclonal
Conjugate
All conjugates for PAK1/2/3 antibodies
This PAK1/2/3 antibody is un-conjugated
Application
All applications for PAK1/2/3 antibodies
Immunohistochemistry (IHC)
Specificity
PAK1/PAK2/PAK3 (Ab-423/402/421) antibody detects endogenous levels of total PAK1/PAK2/PAK3 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human PAK1around the phosphorylation site of threonine 423 (R-S-TP-M-V).
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Alternatives
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Application Details
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Application Notes
IHC: 1:50-1:100.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
100ug/100ul.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
References for anti-PAK1/2/3 antibody (ABIN966799)
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Parsons, Monypenny, Ameer-Beg, Millard, Machesky, Peter, Keppler, Schiavo, Watson, Chernoff, Zicha, Vojnovic, Ng : "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells. " in: Molecular and cellular biology , Vol. 25 , Issue 5 , pp. 1680-95 , (2005 ) (PubMed ).
Lampugnani, Zanetti, Breviario, Balconi, Orsenigo, Corada, Spagnuolo, Betson, Braga, Dejana : "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam. " in: Molecular biology of the cell , Vol. 13 , Issue 4 , pp. 1175-89 , (2002 ) (PubMed ).
Wang, Mazumdar, Vadlamudi, Kumar : "P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium. " in: The EMBO journal , Vol. 21 , Issue 20 , pp. 5437-47 , (2002 ) (PubMed ).
Target Details for PAK1/2/3
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Target
PAK1/2/3
(P21-Activated Kinases 1/2/3 (PAK1/2/3))
Alternative Name
PAK1/PAK2/PAK3 (PAK1/2/3 Products )
Synonyms
X-PAK1 antibody, XPak1 antibody, pak antibody, pak-1 antibody, pakalpha antibody, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antibody, p21 (RAC1) activated kinase 1 antibody, pak1.S antibody, PAK1 antibody
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