Structural Maintenance of Chromosomes 1A (SMC1A) antibody

Details for Product No. ABIN967050
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Antigen
Synonyms smc1a, smc1l1, zgc:76902, im:7158706, SMC1L1, SMC1L2, NV15570, CDLS2, DXS423E, SB1.8, SMC1, SMC1alpha, SMCB, 5830426I24Rik, SMC-1A, Sb1.8, Smc1, Smc1alpha, Smc1l1, Smcb, mKIAA0178, smc1aa, smc1, xSMC1
Reactivity
Human, Mouse (Murine)
(165), (82), (32), (26), (26), (26), (24), (12), (2), (2), (1), (1), (1)
Host
Rabbit
(139), (27), (2), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(133), (63), (43), (38), (30), (19), (15), (9), (9), (7), (3), (1), (1)
Pubmed 3 references available
Quantity 100 μg
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Catalog No. ABIN967050
398.75 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human SMC1 around the phosphorylation site of serine 957 (G-S-SP-Q-G).
Specificity SMC1 (Ab-957) antibody detects endogenous levels of total SMC1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name SMC1
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Revenkova, Eijpe, Heyting et al.: "Novel meiosis-specific isoform of mammalian SMC1." in: Molecular and cellular biology, Vol. 21, Issue 20, pp. 6984-98, 2001 (PubMed).

Kim, Xu, Kastan: "Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage." in: Genes & development, Vol. 16, Issue 5, pp. 560-70, 2002 (PubMed).

Yang, Mehta, Uzri et al.: "Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation." in: Molecular and cellular biology, Vol. 24, Issue 12, pp. 5290-303, 2004 (PubMed).

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