SMC1A antibody

Catalog No. ABIN967050

Cited in 3+ publications. The Rabbit Polyclonal anti-SMC1A antibody (ABIN967050) specifically detects SMC1A in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for SMC1A antibody (ABIN967050)

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC1A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SMC1A Antibody

Specificity: SMC1 (Ab-957) antibody detects endogenous levels of total SMC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human SMC1 around the phosphorylation site of serine 957 (G-S-SP-Q-G).

Application Details

Application Notes: IHC: 1:50-1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-SMC1A antibody (ABIN967050)

Yang, Mehta, Uzri, Jayaram, Velmurugan: "Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation." in: Molecular and cellular biology, Vol. 24, Issue 12, pp. 5290-303, (2004) (PubMed).

Kim, Xu, Kastan: "Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage." in: Genes & development, Vol. 16, Issue 5, pp. 560-70, (2002) (PubMed).

Revenkova, Eijpe, Heyting, Gross, Jessberger: "Novel meiosis-specific isoform of mammalian SMC1." in: Molecular and cellular biology, Vol. 21, Issue 20, pp. 6984-98, (2001) (PubMed).

Target Details for SMC1A

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Alternative Name: SMC1

Pathways: Stem Cell Maintenance