OBFC1 antibody (N-Term)

Catalog No. ABIN967111

This Rabbit Polyclonal antibody specifically detects OBFC1 in IHC. It exhibits reactivity toward Saccharomyces cerevisiae and has been mentioned in 5+ publications.

Quick Overview for OBFC1 antibody (N-Term) (ABIN967111)

Target: OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))

Reactivity: Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OBFC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-OBFC1 Antibody

Binding Specificity: N-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near N-terminal residues of Baker's Yeast (Saccharomyces cerevisiae) STN1 (Protein STN1)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-OBFC1 antibody (ABIN967111)

Albuquerque, Smolka, Payne, Bafna, Eng, Zhou: "A multidimensional chromatography technology for in-depth phosphoproteome analysis." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 7, pp. 1389-96, (2008) (PubMed).

Grandin, Damon, Charbonneau: "Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13." in: The EMBO journal, Vol. 20, Issue 5, pp. 1173-83, (2001) (PubMed).

Chandra, Hughes, Nugent, Lundblad: "Cdc13 both positively and negatively regulates telomere replication." in: Genes & development, Vol. 15, Issue 4, pp. 404-14, (2001) (PubMed).

Grandin, Reed, Charbonneau: "Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13." in: Genes & development, Vol. 11, Issue 4, pp. 512-27, (1997) (PubMed).

Coster, Jonniaux, Goffeau: "Analysis of a 32.8 kb segment of yeast chromosome IV reveals 21 open reading frames, including TPS2, PPH3, RAD55, SED1, PDC2, AFR1, SSS1, SLU7 and a tRNA for arginine." in: Yeast (Chichester, England), Vol. 11, Issue 7, pp. 673-9, (1995) (PubMed).

Target Details for OBFC1

Target: OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))

Alternative Name: STN1

Background: STN1 (Protein STN1) has a role in telomere length regulation and telomere end protection. Acts as an inhibitor of telomerase loading through its interaction with CDC13. STN1 (Protein STN1)interacts with CDC13 and TEN1. STN1 may localize in Telomere and it is similar to YDR082W STN1 Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping.
Synonyms: D4456, YD8554.15