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MAPT antibody (Microtubule-Associated Protein tau)

Details for Product anti-MAPT Antibody No. ABIN967155, Supplier: Login to see New
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Antigen
Synonyms tau, xtp, MAPT, AI426939, AI551861, AW457082, CK1epsilon, CKIe, KC1epsilon, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU, AI413597, AW045860, Mtapt, Tau, PHF-tau, RNPTAU, pTau
Alternatives
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(985), (427), (398), (82), (20), (18), (16), (11), (9), (5), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(936), (109), (11), (9)
Clonality
Polyclonal
Conjugate
This MAPT antibody is un-conjugated
(27), (9), (8), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(885), (350), (294), (104), (94), (69), (44), (22), (14), (12), (12), (12), (12), (11), (6), (3), (2), (1), (1)
Pubmed 3 references available
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Quantity 100 μg
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Tau around the phosphorylation site of serine 235 (P-K-SP-P-S).
Specificity Tau (Ab-235) antibody detects endogenous levels of total Tau protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Tau (MAPT Antibody Abstract)
Pathways MAPK Signaling, Microtubule Dynamics
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Liu, Iqbal, Grundke-Iqbal et al.: "Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta." in: FEBS letters, Vol. 530, Issue 1-3, pp. 209-14, 2002 (PubMed).

Sengupta, Kabat, Novak et al.: "Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules." in: Archives of biochemistry and biophysics, Vol. 357, Issue 2, pp. 299-309, 1998 (PubMed).

Background publications Alonso, Mederlyova, Novak et al.: "Promotion of hyperphosphorylation by frontotemporal dementia tau mutations." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34873-81, 2004 (PubMed).

Catalog No. ABIN967155
$398.75
Plus shipping costs $45.00

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