Tyrosine Kinase 2 (TYK2) antibody

Details for Product No. ABIN967219
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Antigen
Synonyms JTK1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(111), (58), (45), (27), (15), (15), (15), (12)
Host
Rabbit
(89), (21)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(78), (41), (26), (21), (14), (14), (6), (6), (2), (1), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN967219
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human TYK2 around the phosphorylation site of tyrosine 1054 (H-E-YP-Y-R).
Specificity TYK2 (Ab-1054) antibody detects endogenous levels of TYK2 protein around tyrosine 1054.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Tyk2
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Gauzzi, Velazquez, McKendry et al.: "Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20494-500, 1996 (PubMed).

Zheng, Hu, Quinn et al.: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, 2005 (PubMed).

Hosts (89), (21)
Reactivities (111), (58), (45), (27), (15), (15), (15), (12)
Applications (78), (41), (26), (21), (14), (14), (6), (6), (2), (1), (1), (1), (1)
Conjugates (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (29), (14), (6), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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