Tyrosine Kinase 2 (TYK2) antibody

Details for Product No. ABIN967219
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Antigen
Synonyms JTK1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(129), (57), (44), (27), (15), (15), (15), (12), (1)
Host
Rabbit
(103), (25)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (6), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(87), (53), (34), (22), (21), (15), (11), (10), (6), (1)
Pubmed 2 references available
Quantity 100 µg
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Catalog No. ABIN967219
385.00 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human TYK2 around the phosphorylation site of tyrosine 1054 (H-E-YP-Y-R).
Specificity TYK2 (Ab-1054) antibody detects endogenous levels of TYK2 protein around tyrosine 1054.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Tyk2
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Gauzzi, Velazquez, McKendry et al.: "Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20494-500, 1996 (PubMed).

Zheng, Hu, Quinn et al.: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, 2005 (PubMed).

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