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Tyrosine Kinase 2 (TYK2) antibody

Antigen

Tyrosine Kinase 2 (TYK2)
Synonyms JTK1, TYK2, FLJ12949
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
2 references available
Catalog no. ABIN967219
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name Tyk2
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human TYK2 around the phosphorylation site of tyrosine 1054 (H-E-YP-Y-R).
Specificity TYK2 (Ab-1054) antibody detects endogenous levels of TYK2 protein around tyrosine 1054.

Application Details
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Application Notes IHC: 1:50-1:100.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
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Product Gauzzi, Velazquez, McKendry et al.: "Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20494-500, 1996 (PubMed).

Zheng, Hu, Quinn et al.: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, 2005 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Tyrosine Kinase 2 (TYK2)", type "Antibodies"
Hosts Rabbit (78), Mouse (12)
Reactivities Human (88), Mouse (Murine) (58), Rat (Rattus) (32), Dog (Canine) (24), Chicken (19), Cow (Bovine) (19), Pig (Porcine) (19)
Applications Western Blotting (WB) (46), ELISA (28), Immunofluorescence (IF) (28), Flow Cytometry (FACS) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Immunohistochemistry (IHC) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunoprecipitation (IP) (5), Immunocytochemistry (ICC) (3), Immunoelectron Microscopy (IEM) (2)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy7 (2), Alexa Flour 488 (1)
Epitopes pTyr1054 (6), pTyr1055,pTyr1054 (4), C-Term (3), Internal Region (3), pTyr292,Internal Region (3), N-Term (2), Tyr1054 (2), pTyr1054, pTyr1055 (2), AA 249-396 (1), pThr184 (1)