anti-TYK2 antibody (Tyrosine Kinase 2)

Details for Product anti-TYK2 Antibody No. ABIN967219, Supplier: Login to see New
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Antigen
Synonyms JTK1
Alternatives
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(176), (67), (49), (1)
Host
Rabbit
(150), (26)
Clonality
Polyclonal
Conjugate
This TYK2 antibody is un-conjugated
(6), (6), (6), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(104), (66), (55), (25), (25), (24), (9), (6), (1), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human TYK2 around the phosphorylation site of tyrosine 1054 (H-E-YP-Y-R).
Specificity TYK2 (Ab-1054) antibody detects endogenous levels of TYK2 protein around tyrosine 1054.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Tyk2 (TYK2 Antibody Abstract)
Pathways JAK-STAT Signaling
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Zheng, Hu, Quinn et al.: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, 2005 (PubMed).

Gauzzi, Velazquez, McKendry et al.: "Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20494-500, 1996 (PubMed).

Catalog No. ABIN967219
$398.75
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