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SCARB1 antibody (Scavenger Receptor Class B, Member 1) (AA 104-294)

Details for Product anti-SCARB1 Antibody No. ABIN968230, Supplier: Login to see New
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Synonyms cb1015, SCARB1, Scarb1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1, AI120173, CD36, Cd36l1, Cla-1, Cla1, D5Ertd460e, Hdlq1, Hlb398, SR-B1, SRBI, Srb1, mSR-BI
AA 104-294
(23), (15), (9), (5), (2), (2), (1), (1), (1), (1), (1), (1), (1)
(57), (32), (27), (2)
(54), (14), (7)
Clonality (Clone)
Monoclonal ()
This SCARB1 antibody is un-conjugated
(4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Immunofluorescence (IF), Western Blotting (WB)
(58), (26), (24), (19), (9), (7), (6), (6), (5), (2), (2), (1), (1)
Pubmed 4 references available
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Quantity 50 μg
Shipping to United States ( )
Immunogen Human CLA-1 aa. 104-294
Clone 25-CLA
Isotype IgG1
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name CLA-1 (SCARB1 Antibody Abstract)
Background CLA-1 (CD36 and LIMPII Analogous-1) is member of a novel gene family that includes CD36, LIMPII, and SR-BI. CD36 is a cell surface glycoprotein that binds to collagen type I and thrombospondin. LIMPII (lysosomal integral membrane protein II), as its name suggests, is expressed on the membrane of lysosomes. SR-BI (scavenger receptor type B class I) is involved in the selective uptake of cholesterol esters. These proteins include two membrane-anchoring regions, two short cytoplasmic tails, and a large extracellular/luminal domain. CLA-1 mRNA is detected in a wide range of tissues including adrenal glands, liver, and testis. Its expression and similarity with other family members suggest it may play a role in HDL metabolism. However, identification of the CLA-1 receptor on monocytes indicates additional CLA-1 functions in leukocytes.
Synonyms: CD36 and LIMPII Analogous-1
Molecular Weight 80 kDa

Related Products: ABIN968535, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20°C.
Supplier Images
Western Blotting (WB) image for anti-SCARB1 antibody (Scavenger Receptor Class B, Member 1) (AA 104-294) (ABIN968230) Western blot analysis of CLA-1 on a HeLa cell lysate (Human cervical epitheloid carci...
Immunofluorescence (IF) image for anti-SCARB1 antibody (Scavenger Receptor Class B, Member 1) (AA 104-294) (ABIN968230) Immunofluorescence staining of human endothelial cells.
Product cited in: Lasley, Narayan, Uittenbogaard et al.: "Activated cardiac adenosine A(1) receptors translocate out of caveolae." in: The Journal of biological chemistry, Vol. 275, Issue 6, pp. 4417-21, 2000 (PubMed).

Kozarsky, Donahee, Rigotti et al.: "Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels." in: Nature, Vol. 387, Issue 6631, pp. 414-7, 1997 (PubMed).

Acton, Rigotti, Landschulz et al.: "Identification of scavenger receptor SR-BI as a high density lipoprotein receptor." in: Science (New York, N.Y.), Vol. 271, Issue 5248, pp. 518-20, 1996 (PubMed).

Calvo, Vega: "Identification, primary structure, and distribution of CLA-1, a novel member of the CD36/LIMPII gene family." in: The Journal of biological chemistry, Vol. 268, Issue 25, pp. 18929-35, 1993 (PubMed).

Catalog No. ABIN968230
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