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Cerberus 1 Homolog (Xenopus Laevis) (CER1) antibody

Details for Product No. ABIN969050, Supplier: Log in to see
Antigen
  • DAND4
Reactivity
Human
41
2
Host
Mouse
26
15
Clonality (Clone)
Monoclonal ()
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
38
21
10
7
2
2
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Immunogen Purified recombinant fragment of human CER1 expressed in E. coli.
Clone 9D6
Isotype IgG1
Purification Ascites
Alternative Name CER1 (CER1 Antibody Abstract)
Background CER1: cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis). Ii is a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity.
Molecular Weight 30 kDa
Gene ID 9350
HGNC 9350
Pathways
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunohistochemistry (IHC) image for anti-Cerberus 1 Homolog (Xenopus Laevis) (CER1) antibody (ABIN969050) Figure 1: Immunohistochemical analysis of paraffin-embedded human gastric cancer (lef...
Western Blotting (WB) image for anti-Cerberus 1 Homolog (Xenopus Laevis) (CER1) antibody (ABIN969050) Figure 2: Western blot analysis using CER1 mouse mAb against CER1 (aa18-267) -hIgGFc ...
Product cited in: Young, Hopkins, Hay et al.: "Lung cancer susceptibility model based on age, family history and genetic variants." in: PLoS ONE, Vol. 4, Issue 4, pp. e5302, 2009 (PubMed).

Chen, Zhao, Mundy: "Bone morphogenetic proteins." in: Growth factors (Chur, Switzerland), Vol. 22, Issue 4, pp. 233-41, 2004 (PubMed).

Background publications Biben, Stanley, Fabri et al.: "Murine cerberus homologue mCer-1: a candidate anterior patterning molecule." in: Developmental biology, Vol. 194, Issue 2, pp. 135-51, 1998 (PubMed).