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Details for Product No. ABIN969091

Epidermal Growth Factor (EGF) antibody

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Antigen
Synonyms CEGF, URG, HOMG4, AI790464
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN969091
Quantity 100 µL
Price
363.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human EGF expressed in E. coli.
Clone 9D7F11
Isotype IgG1
Purification Ascites
Alternative Name EGF
Background Synonyms:
URG, HOMG4, EGF
Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53 AA peptide hormone that stimulates cells to divide.
Molecular Weight 134 kDa
Gene ID 1950
Research Area Cancer, Growth Factors
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Soubeyran, Kowanetz, Szymkiewicz et al.: "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors." in: Nature, Vol. 416, Issue 6877, pp. 183-7, 2002 (PubMed).

Yacoub, McKinstry, Hinman et al.: "Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling." in: Radiation research, Vol. 159, Issue 4, pp. 439-52, 2003 (PubMed).

Alternatives for antigen "Epidermal Growth Factor (EGF)", type "Antibodies"
Hosts (181), (109), (18), (4), (4), (1)
Reactivities (186), (98), (65), (6), (6), (4), (4), (1), (1), (1)
Applications (194), (174), (62), (60), (46), (31), (23), (15), (11), (10), (9), (9), (7), (6), (5), (4), (3), (2), (2), (2)
Conjugates (36), (11), (9), (6), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (4), (4)
Epitopes (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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