Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) antibody

Details for Product No. ABIN969097
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Antigen
Synonyms NOS3, ECNOS, eNOS, NOS, EC-NOS, NOSIII, cNOS, 2310065A03Rik, Nos-3, ecNOS, eNos, ENOS
Reactivity
Human
(315), (203), (199), (80), (69), (65), (37), (3), (2), (1), (1), (1)
Host
Mouse
(335), (21)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(17), (12), (12), (8), (8), (8), (8), (8), (8), (8), (8), (3), (3), (3)
Application
ELISA, Immunohistochemistry (IHC)
(224), (137), (80), (70), (48), (29), (29), (12), (12), (10), (9), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 µL
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Catalog No. ABIN969097
363.00 $
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Immunogen Purified recombinant fragment of human eNOS expressed in E. coli.
Clone 6H2
Isotype IgG1
Purification Ascites
Alternative Name eNOS
Background Synonyms:
ECNOS, NOS3
Endothelial nitric-oxide synthase (eNOS), also known as NOS3, it is an important enzyme in the cardiovascular system. It is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm.
Molecular Weight 133 kDa
Gene ID 4846
Research Area Cancer, Enzymes, Metabolism, Inflammation
Application Notes Recommended Dilution:
ELISA: 1/10000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) antibody Figure 2: Immunohistochemical analysis of paraffin-embedded human stomach cancer (left) and ovary cancer (right) tissues using eNOS mouse mAb with DAB staining.
anti-Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) antibody (2) Figure 1: Immunohistochemical analysis of paraffin-embedded human lymph node (left) and colon cancer (right) tissues using eNOS mouse mAb with DAB staining.
Product cited in: Dimmeler, Fleming, Fisslthaler et al.: "Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation." in: Nature, Vol. 399, Issue 6736, pp. 601-5, 1999 (PubMed).

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