ENOS antibody (pSer1177)

Catalog No. ABIN746468

There are 4+ publications for this product available. The Rabbit Polyclonal anti-ENOS antibody is suitable to detect ENOS in samples from Human. It has been validated for WB.

Quick Overview for ENOS antibody (pSer1177) (ABIN746468)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENOS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ENOS Antibody

Binding Specificity: pSer1177

Purpose: Phospho-eNOS (Ser1177) Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from mouse eNOS around the phosphorylation site of Ser1177

Isotype: IgG

Application Details

Application Notes: WB(1:500-1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ENOS antibody (ABIN746468)

Chen, Tan, Wu, Chai, Yeh, Chou, Chen, Dai: "Statins ameliorate pulmonary hypertension secondary to left ventricular dysfunction through the Rho-kinase pathway and NADPH oxidase." in: Pediatric pulmonology, Vol. 52, Issue 4, pp. 443-457, (2016) (PubMed).

Yin, Wan, Li, Jia, Sun, Pan, Wan: "Protective effect of Xin Mai Jia ultrafiltration extract on human umbilical vein endothelial cell injury induced by hydrogen peroxide and the effect on the NO-cGMP signaling pathway." in: Experimental and therapeutic medicine, Vol. 8, Issue 1, pp. 38-48, (2014) (PubMed).

Ikemura, Yamamoto, Motomura, Yamaguchi, Zhao, Iwasaki, Iwamoto: "Preventive effects of the anti-vasospasm agent via the regulation of the Rho-kinase pathway on the development of steroid-induced osteonecrosis in rabbits." in: Bone, Vol. 53, Issue 2, pp. 329-35, (2013) (PubMed).

Chuang, Lin, Huang, Chang, Liou, Chen, Chang, Chan et al.: "Peroxisome proliferator-activated receptors ?/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status ..." in: Journal of neuroinflammation, Vol. 9, pp. 184, (2012) (PubMed).

Target Details for ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Alternative Name: eNOS

Background: Synonyms: eNOS(phospho S1177), eNOS(phospho S1177), p-eNOS(phospho S1177), eNOS(phospho-Ser1177), cNOS, Constitutive NOS, EC NOS, ecNOS, Endothelial nitric oxidase synthase, Endothelial nitric oxide synthase, Endothelial nitric oxide synthase 3, Endothelial NOS, Nitric oxide synthase 3(endothelial cell), Nitric oxide synthase 3, Nitric oxide synthase 3 endothelial cell, Nitric oxide synthase endothelial, nitric oxide synthase, endothelial, NOS 3, NOS III, NOS type III, NOS3, NOSIII, NOS3_HUMAN.

Gene ID: 4846

UniProt: P70313

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling