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Details for Product No. ABIN969226

Lysyl-tRNA Synthetase (KARS) (AA 90-174) antibody

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Antigen
Synonyms
CMTRIB, DFNB89, KARS1, KARS2, KRS, LysRS, AA589550, AL024334, AL033315, AL033367, D8Wsu108e, mKIAA0070, D8Ertd698e, CG12141, Dmel\\CG12141, cb530, wu:fa16h02, zgc:92483, kars, MGC53345, kars2, krs, kr ... show more
Epitope
»Alternatives AA 90-174
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 4 references available
Catalog no. ABIN969226
Quantity 100 µL
Price
363.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of KARS (AA 90-174) expressed in E. coli.
Clone 8G12C1
Isotype IgG1
Purification Ascites
Alternative Name KARS
Background Synonyms:
KRS, KARS2, KIAA0070
KARS: lysyl-tRNA synthηse. Aminoacyl-tRNA synthηses are a class of enzymes that charge tRNAs with their cognate AA. Lysyl-tRNA synthηse is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthηses. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Gene ID 3735
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Tolkunova, Park, Xia et al.: "The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35063-9, 2000 (PubMed).

Cen, Khorchid, Javanbakht et al.: "Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1." in: Journal of virology, Vol. 75, Issue 11, pp. 5043-8, 2001 (PubMed).

Sang Lee, Gyu Park, Park et al.: "Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex." in: Biochemical and biophysical research communications, Vol. 291, Issue 1, pp. 158-64, 2002 (PubMed).

Sampath, Mazumder, Seshadri et al.: "Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation." in: Cell, Vol. 119, Issue 2, pp. 195-208, 2004 (PubMed).

Alternatives for antigen "Lysyl-tRNA Synthetase (KARS)", type "Antibodies"
Hosts (30), (7)
Reactivities (34), (19), (15), (13), (12), (12), (12)
Applications (28), (14), (10), (8), (8), (4), (3), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (3), (2), (2), (2), (1)
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